Bifidobacterium animalis subsp. lactis BB-12 and Reduced Upper Respiratory Infections

• Bifidobacterium animalis subsp. lactis BLa80 for preventing allergic, respiratory, and gastrointestinal diseases in young children in China: a randomized double-blind placebo-controlled trial.

  • 2026-02-15
  • RCT · n = 180
  • Clinical and experimental pediatrics 69(2)
  • • Ke Chen
    • Xi Zhang
    • Kaihong Zeng
    • Jiayi Zhong
    • Shanshan Jin
    • Yang Nie
    • Ping Yang
    • Nianyang He
    • Haixia Chen
    • Yanmei Cao
    • Yunrong Fu
    • Ziji Fang
    • Wei Jiang
    • Changqi Lium

  • PubMed: 41167178
  • DOI: 10.3345/cep.2025.01256

  6 Insights on

  • Reduced Upper Respiratory Infections

  • High evidence

  Probiotic supplementation was also associated with a lower risk of URTIs (IG vs. CG: 40.3% vs. 20.7%; risk ratio [RR], 0.752; 95% confidence interval [CI], 0.653-0.866).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes