Bifidobacterium animalis subsp. lactis Bi-07 and Probiotic Detection

• Comparison of qRT-PCR and ddPCR for multi-strain probiotic detection after a randomized human clinical trial.

  • 2025-04-28
  • Clinical Trial
  • Frontiers in microbiology 16
  • • Nicolas Yeung
    • Arthur C Ouwehand

  • PubMed: 40356649
  • DOI: 10.3389/fmicb.2025.1579797

  3 Insights on

  • Probiotic Detection

  • Moderate evidence

  The ability to detect probiotic consumption during a human clinical trial is crucial to verify and validate placebo and verum groups in post hoc analysis... we aimed to detect the components of a multi-strain probiotic product from a human clinical trial and compare both methods.

  Effect

  Neutral

  Effect size

  Small

• Development of a Strain-Specific Detection and Quantification Method for Bifidobacterium animalis subsp. lactis HN019 Using WGS-SNP Analysis and qPCR.

  • 2025-07-07
  • Microorganisms 13(7)
  • • Da Mao
    • Lei Zhao
    • Bo Zhao
    • Hongbin Xu
    • Qinghe Zhang

  • PubMed: 40732105
  • DOI: 10.3390/microorganisms13071596

  6 Insights on

  • Probiotic Detection

  • Low evidence

  Successful quantification of HN019 in complex multi-strain probiotic powders confirmed its practical reliability.

  Effect

  Beneficial

  Effect size

  Moderate