Bifidobacterium animalis subsp. lactis Bi-07 and Reduced Breath Hydrogen Production

• Bifidobacterium animalis subsp. lactis Bi-07 supports lactose digestion in vitro and in randomized, placebo- and lactase-controlled clinical trials

  • 2022-12
  • RCT
  • The American Journal of Clinical Nutrition 116(6)
  • • Pia Rasinkangas
    • S. Forssten
    • M. Marttinen
    • A. Ibarra
    • G. Bothe
    • J. Junnila
    • R. Uebelhack
    • Y. Donazzolo
    • A. Ouwehand

  • PubMed: 36149331
  • DOI: 10.1093/ajcn/nqac264

  3 Insights on

  • Reduced Breath Hydrogen Production

  • High evidence

  Bi-07 was superior to placebo in reducing BHC [iAUC, parts per million (ppm) ∙ h] in both trials (Booster Alpha: geometric least square mean ratio: 0.462; 95% CI: 0.249, 0.859; P = 0.016; Booster Omega: 0.227; 95% CI: 0.095, 0.543; P = 0.001).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes