Bifidobacterium animalis subsp. lactis Bi-07 and Reduced Proinflammatory Cytokine Secretion

• Xylo-oligosaccharides alone or in synbiotic combination with Bifidobacterium animalis subsp. lactis induce bifidogenesis and modulate markers of immune function in healthy adults: a double-blind, placebo-controlled, randomised, factorial cross-over study

  • 2014-03-24
  • RCT
  • British Journal of Nutrition 111(11)
  • • C. Childs
    • H. Röytiö
    • E. Alhoniemi
    • Á. Fekete
    • S. Forssten
    • Natasa Hudjec
    • Ying Ni Lim
    • Cara J Steger
    • P. Yaqoob
    • K. Tuohy
    • R. Rastall
    • A. Ouwehand
    • G. Gibson

  • PubMed: 24661576
  • DOI: 10.1017/S0007114513004261

  5 Insights on

  • Reduced Proinflammatory Cytokine Secretion

  • High evidence
  • Highly Cited

  Bi-07 supplementation significantly ... lowered lipopolysaccharide-stimulated IL-4 secretion in whole-blood cultures (P= 0·035)

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

  Dose

  10^9 CFU/d