Bifidobacterium animalis subsp. lactis BPL1 and Improved Insulin Sensitivity

• Effects of Bifidobacterium animalis Subsp. lactis (BPL1) Supplementation in Children and Adolescents with Prader-Willi Syndrome: A Randomized Crossover Trial.

  • 2020-10-13
  • RCT · n = 39
  • Nutrients 12(10)
  • • Montse Amat-Bou
    • Sonika Garcia-Ribera
    • Eric Climent
    • Irene Piquer-Garcia
    • Raquel Corripio
    • David Sanchez-Infantes
    • Laia Villalta
    • Maria Elias
    • Josep C Jiménez-Chillarón
    • Empar Chenoll
    • Daniel Ramón
    • Lourdes Ibañez
    • Marta Ramon-Krauel
    • Carles Lerin

  • PubMed: 33066107
  • DOI: 10.3390/nu12103123

  8 Insights on

  • Improved Insulin Sensitivity

  • High evidence
  • Rigorous Journal
  • Clinical

  BPL1 improved fasting insulin concentration and insulin sensitivity

  Effect

  Beneficial

  Effect size

  Small

  Significant

  Yes

• Oral lipoteichoic and lipoic acids improve insulin resistance and body composition in porphyria mice on a high-carbohydrate diet.

  • 2025-09-26
  • n = 6
  • Journal of physiology and biochemistry 81(4)
  • • Miriam Longo
    • Teresa Rubio
    • Araceli Lamelas
    • Daniel Jericó
    • Andrea Rodenes-Gavidia
    • Jordi Cervero
    • Juan Martínez-Blanch
    • Empar Chenoll
    • Patricia Martorell
    • Erika Paolini
    • Marica Meroni
    • José Ignacio Riezu-Boj
    • Isabel Solares
    • Ana Sampedro
    • Francesco Urigo
    • María Collantes
    • Michele Battistin
    • Stefano Gatti
    • Gemma Quincoces
    • Ivan Peñuelas
    • María Jesús Moreno-Aliaga
    • Matías A Ávila
    • Elena Di Pierro
    • Daniel Ramón
    • Fermín I Milagro
    • Paola Dongiovanni
    • Antonio Fontanellas

  • PubMed: 41004024
  • DOI: 10.1007/s13105-025-01124-4

  3 Insights on

  • Improved Insulin Sensitivity

  • Low evidence
  • Animal Study

  Supplementation with α-LA and LTA revealed superior ability to improve glucose tolerance test and skeletal muscle glucose uptake, reduce hyperinsulinemia

  Effect

  Beneficial

  Effect size

  Moderate