Effects of oral administration of Bifidobacterium animalis subsp. lactis HN019 on the treatment of plaque-induced generalized gingivitis.
- 2022-10-28
- RCT · n = 30
- Clinical oral investigations 27(1)
- Yara Loyanne de Almeida Silva Levi
- Marcella Costa Ribeiro
- Pedro Henrique Félix Silva
- Giselle Aparecida Silva
- Sergio Luiz de Souza Salvador
- Sérgio Luís Scombatti de Souza
- Renato Casarin
- Arthur Belem Novaes Júnior
- Mario Taba Júnior
- Daniela Bazan Palioto
- Heitor Marques Honório
- Michel Reis Messora
- Flávia Aparecida Chaves Furlaneto
- PubMed: 36305963
- DOI: 10.1007/s00784-022-04744-y
- High evidence
The test group presented significantly lower levels of IL-1α, IL-1β, and MCP-1 in GCF than the control group at the end of the study (p < 0.05).
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes
- Dose
- probiotic lozenges consumed twice a day for 8 weeks