Interconnection of the Gut-Skin Axis in NC/Nga Mouse with Atopic Dermatitis: Effects of the Three Types of Bifidobacterium bifidum CBT-BF3 (Probiotics, Postbiotics, and Cytosine-Phosphate-Guanine Oligodeoxynucleotide) on T Cell Differentiation and Gut Microbiota.
- 2024-11
- Clinical Trial
- Food science of animal resources 44(6)
- Gwang Il Kim
- Hwa Yeong Jeong
- In Sung Kim
- Seung Ho Lee
- Sung Hak Kim
- Yang Soo Moon
- Kwang Keun Cho
- PubMed: 39554831
- DOI: 10.5851/kosfa.2024.e100
- Moderate evidence
oral administration of the three types of B. bifidum (probiotics, postbiotics, CpG ODN) to AD mice decreased the mRNA expression levels of Th2 and Th17 cell transcription factors and cytokines as well as TSLP cytokine. They increased the mRNA expression levels of regulatory T (Treg) cell transcription factor and cytokine, galectin-9, and filaggrin genes
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes