Bifidobacterium bifidum G9-1 and Increased Intestinal IgA Secretion

• Peptidoglycan from Bifidobacterium bifidum G9-1 induces IgA secretion in Peyer's patch-derived cells.

  • 2026-01-06
  • Bioscience of microbiota, food and health 45(1)
  • • Hiroaki Konishi
    • Koji Yamamoto
    • Aki Sakatani
    • Tatsuya Dokoshi
    • Yutaka Makizaki
    • Yoshiki Tanaka
    • Hiroshi Ohno
    • Kentaro Moriichi
    • Mikihiro Fujiya

  • PubMed: 41492380
  • DOI: 10.12938/bmfh.2025-040

  1 Insight on

  • Increased Intestinal IgA Secretion

  • Low evidence

  Heat-killed BBG9-1, but not its culture supernatant, significantly enhanced IgA secretion and cell aggregation.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes