Bifidobacterium bifidum Rosell-71 and Reduced Depression Symptoms

• Role of Probiotics in Management of Depressive Symptoms and Cognitive Impairment in Patients With Depression: An Updated Analysis of Trials.

  • 2025-11-29
  • Meta-Analysis
  • Brain and behavior 15(12)
  • • Syed Ali Arsal
    • Aashish Kumar
    • Umer Iqbal
    • Shafin Bin Amin
    • Muhammad Aniq Amir
    • Muhammad Abrar Amir
    • Muhammad Ashir Shafique
    • Suhaib Ahmed
    • Laksh Kumar
    • Oluwatobiloba Israel Popoola
    • Inibehe Ime Okon

  • PubMed: 41319022
  • DOI: 10.1002/brb3.71108

  2 Insights on

  • Reduced Depression Symptoms

  • High evidence

  the probiotic group had a significant reduction in depressive symptoms compared to the placebo group (p = 0.03; SMD, -0.55; 95% CI, -1.04 to -0.06; I2 = 79%)

  • Beneficial
  • Moderate effect
  • Significant

• Probiotics as Modulators of Adult Neurogenesis and Synaptic Plasticity: New Perspectives in the Pathophysiology and Treatment of Affective Disorders.

  • 2026-03-12
  • Review
  • Biomedicines 14(3)
  • • Gilberto Uriel Rosas-Sánchez
    • León Jesús Germán-Ponciano
    • María Isabel Pérez-Vega
    • Oscar Gutiérrez-Coronado
    • José Luis Muñoz-Carrillo
    • Alejandro David Soriano-Hernández
    • Abril Alondra Barrientos-Bonilla
    • Carmen Gabriela Rosales-Muñoz
    • Cesar Soria-Fregozo

  • PubMed: 41898284
  • DOI: 10.3390/biomedicines14030637

  4 Insights on

  • Reduced Depression Symptoms

  • Low evidence

  Clinical evidence from randomized controlled trials and recent meta-analyses indicates that probiotic supplementation produces significant reductions in depressive and anxiety symptoms

  • Beneficial
  • Moderate effect
  • Significant

• Probiotics' Effects in the Treatment of Anxiety and Depression: A Comprehensive Review of 2014-2023 Clinical Trials.

  • 2024-02-19
  • Review
  • Microorganisms 12(2)
  • • Ermis Merkouris
    • Theodora Mavroudi
    • Daniil Miliotas
    • Dimitrios Tsiptsios
    • Aspasia Serdari
    • Foteini Christidi
    • Triantafyllos K Doskas
    • Christoph Mueller
    • Konstantinos Tsamakis

  • PubMed: 38399815
  • DOI: 10.3390/microorganisms12020411

  2 Insights on

  • Reduced Depression Symptoms

  • Low evidence

  the majority of the most recent literature suggests a beneficial role of probiotics in the treatment of depression and anxiety

  • Beneficial
  • Moderate effect