Bifidobacterium bifidum VPro 51 and Reduced Severity of Common Cold Symptoms

• Effect of Lactobacillus gasseri PA 16/8, Bifidobacterium longum SP 07/3, B. bifidum MF 20/5 on common cold episodes: a double blind, randomized, controlled trial.

  • 2005-08
  • RCT · n = 122
  • Clinical Nutrition 24(4)
  • • M. de Vrese
    • P. Winkler
    • P. Rautenberg
    • T. Harder
    • C. Noah
    • C. Laue
    • S. Ott
    • J. Hampe
    • S. Schreiber
    • K. Heller
    • J. Schrezenmeir

  • PubMed: 16054520
  • DOI: 10.1016/J.CLNU.2005.02.006

  18 Insights on

  • Reduced Severity of Common Cold Symptoms

  • High evidence
  • Highly Cited

  The total symptom score, the duration of common cold episodes, and days with fever during an episode were lower in the probiotic-treated group than in the control group: 79.3+/-7.4 vs. 102.5+/-12.2 points (P = 0.056), 7.0+/-0.5 vs. 8.9+/-1.0 days (P = 0.045), 0.24+/-0.1 vs. 1.0+/-0.3 days (P = 0.017).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  No