Bifidobacterium breve BR03 and Improved Insulin Sensitivity

• Supplementation with Bifidobacterium breve BR03 and B632 strains improved insulin sensitivity in children and adolescents with obesity in a cross-over, randomized double-blind placebo-controlled trial.

  • 2021-07
  • RCT · n = 101
  • Clinical Nutrition 40(7)
  • • Arianna Solito
    • Nicole Bozzi Cionci
    • M. Calgaro
    • M. Caputo
    • L. Vannini
    • Iderina Hasballa
    • Francesca Archero
    • E. Giglione
    • R. Ricotti
    • G. Walker
    • A. Petri
    • Emanuela Agosti
    • G. Bellomo
    • G. Aimaretti
    • G. Bona
    • S. Bellone
    • A. Amoruso
    • M. Pane
    • D. Di Gioia
    • N. Vitulo
    • F. Prodam

  • PubMed: 34229263
  • DOI: 10.1016/j.clnu.2021.06.002

  6 Insights on

  • Improved Insulin Sensitivity

  • High evidence

  Probiotics improved insulin sensitivity at fasting (QUICKI, 0.013 CI95%0.0-0.03) and during OGTT (ISI, 0.654 CI95%-0.11-1.41).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  No