Tolerance development in cow's milk-allergic infants receiving amino acid-based formula: A randomized controlled trial.
- 2022-02
- RCT · n = 89
- The Journal of allergy and clinical immunology 149(2)
- Pantipa Chatchatee
- Anna Nowak-Wegrzyn
- Lars Lange
- Suwat Benjaponpitak
- Kok Wee Chong
- Pasuree Sangsupawanich
- Marleen T J van Ampting
- Manon M Oude Nijhuis
- Lucien F Harthoorn
- Jane E Langford
- Jan Knol
- Karen Knipping
- Johan Garssen
- Valerie Trendelenburg
- Robert Pesek
- Carla M Davis
- Antonella Muraro
- Mich Erlewyn-Lajeunesse
- Adam T Fox
- Louise J Michaelis
- Kirsten Beyer
- PubMed: 34224785
- DOI: 10.1016/j.jaci.2021.06.025
- High evidence
- Infants
At 12 and 24 months, respectively, 49% and 62% of subjects were CM tolerant (AAF-S 45% and 64%; AAF 52% and 59%), and not differ significantly between groups.
- Effect
- Neutral
- Effect size
- Small
- Significant
- No