Administration of Bifidobacterium breve Improves the Brain Function of Aβ1-42-Treated Mice via the Modulation of the Gut Microbiome
- 2021-05-11
- Clinical Trial
- Nutrients 13(5)
- G. Zhu
- Jianxin Zhao
- Hao Zhang
- Wei Chen
- Gang Wang
- PubMed: 34064762
- DOI: 10.3390/nu13051602
- Low evidence
- Animal Study
Furthermore, the microbiome and metabolomic profiles of mice indicate that specific bacterial taxa and their metabolites correlate with AD-associated behaviors, suggesting that the gut-brain axis contributes to the pathophysiology of AD.
- Effect
- Beneficial
- Effect size
- Moderate