Adjudicative efficacy of Bifidobacterium animalis subsp. lactis BLa80 in treating acute diarrhea in children: a randomized, double-blinded, placebo-controlled study.
- 2024-03-11
- RCT · n = 58
- European journal of clinical nutrition 78(6)
- Ke Chen
- Shanshan Jin
- Yu Ma
- Limei Cai
- Ping Xu
- Yang Nie
- Li Luo
- Qinghua Yu
- Yang Shen
- Zengyuan Zhou
- Changqi Liu
- PubMed: 38467857
- DOI: 10.1038/s41430-024-01428-6
- High evidence
- Rigorous Journal
- Clinical
More children in the IG showed improvements in diarrhea compared to the CG, both in intention-to-treat analysis (81.7% vs. 40.0%, p < 0.001) and per protocol analysis (84.4% vs 45.3%, p < 0.001).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 5 × 10^9 CFU/day