Best Supplements for Reduced Diarrhea Rate
Ranked by research evidence. Compare 32 supplements across 59 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- High evidence11 studies
Across 11 studies, 8 reported beneficial effects of Lactobacillus reuteri DSM 17938 on reducing diarrhea, with effect sizes ranging from small to large. The evidence predominantly comes from children with acute gastroenteritis or in daycare settings, with doses typically around 1–4 × 10^8 CFU/day. Median study duration was 5 days (reported in only 1 of 11 studies), indicating short-term use.
Dose: 1 × 10^8 to 4 × 10^8 CFU/dayProduct matchBioGaia — Kids, Immune Active with L. Reuteri + Vitamin D, Orange· $26.99 · ★4.8 (510) - Moderate evidence10 studies
Across 10 studies, 8 reported beneficial effects of Saccharomyces boulardii on reducing diarrhea rates, with 2 showing neutral findings and none harmful. Effect sizes ranged from small to large, with a moderate effect size most common. The evidence primarily comes from children with acute gastroenteritis or Helicobacter pylori infection, with a median study duration of 60 days reported in one study. Most studies did not specify a consistent dose, though doses of 250 mg to 500 mg/day appeared frequently.
Dose: 250 mg/day to 500 mg/day (capsule form) - Low evidence3 studies
Across 3 studies, all reported beneficial small-to-moderate effects of Saccharomyces boulardii on reducing diarrhea rates, with 3 of 3 showing statistically significant findings. The most-studied population appears to be children with acute diarrhea and adults with SIBO, with doses ranging from 500 mg twice daily to unspecified amounts. Effects were predominantly small, and the median study duration was 35 days.
Dose: 500 mg twice daily
- HighLactobacillus reuteri DSM 17938Across 11 studies, 8 reported beneficial effects of Lactobacillus reuteri DSM 17938 on reducing diarrhea, with effect sizes ranging from small to large. The evidence predominantly comes from children with acute gastroenteritis or in daycare settings, with doses typically around 1–4 × 10^8 CFU/day. Median study duration was 5 days (reported in only 1 of 11 studies), indicating short-term use. · Dose: 1 × 10^8 to 4 × 10^8 CFU/day8 beneficial3 neutral11 studies
- Moderatesaccharomyces boulardiiAcross 10 studies, 8 reported beneficial effects of Saccharomyces boulardii on reducing diarrhea rates, with 2 showing neutral findings and none harmful. Effect sizes ranged from small to large, with a moderate effect size most common. The evidence primarily comes from children with acute gastroenteritis or Helicobacter pylori infection, with a median study duration of 60 days reported in one study. Most studies did not specify a consistent dose, though doses of 250 mg to 500 mg/day appeared frequently. · Dose: 250 mg/day to 500 mg/day (capsule form)8 beneficial2 neutral10 studies
- LowSaccharomyces boulardiiAcross 3 studies, all reported beneficial small-to-moderate effects of Saccharomyces boulardii on reducing diarrhea rates, with 3 of 3 showing statistically significant findings. The most-studied population appears to be children with acute diarrhea and adults with SIBO, with doses ranging from 500 mg twice daily to unspecified amounts. Effects were predominantly small, and the median study duration was 35 days. · Dose: 500 mg twice daily3 beneficial3 studies