Randomized, direct comparison study of Saccharomyces boulardii CNCM I-745 versus multi-strained Bacillus clausii probiotics for the treatment of pediatric acute gastroenteritis
- 2022-09-09
- RCT · n = 317
- Medicine 101(36)
- J. Altcheh
- Mabel V. Carosella
- A. Ceballos
- Ulises D’Andrea
- Sandra M. Jofre
- Carolina R. Marotta
- Domingo Mugeri
- Liliana Sabbaj
- A. Soto
- C. Josse
- F. Montestruc
- L. Mcfarland
- PubMed: 36086703
- DOI: 10.1097/MD.0000000000030500
- High evidence
- Large Human Trial
S boulardii CNCM I-745 showed a significant reduction (P = .04) in the mean duration of diarrhea (64.6 hours, 95% confidence interval [CI] 56.5-72.8) compared to those given B clausii (78.0 hours, 95% CI 69.9-86.1).
- Effect
- Beneficial
- Effect size
- Small
- Significant
- Yes
- Dose
- not stated