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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Bifidobacterium lactis HN019 and Increased PMN Cell Phagocytic Capacity

Doses used in studies

CFU/day: 300 billion (median 300 billion, IQR 300 billion–300 billion) — 1 study

2 of 2 papers

Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses
- 2000-11-01
- RCT · n = 50
- European Journal of Clinical Nutrition 54(11)
- - B. Chiang
  - Y. Sheih
  - LH Wang
  - Chuh-K. Liao
  - H. Gill
- PubMed: 11114680
- DOI: 10.1038/sj.ejcn.1601093
16 Insights on
- Increased PMN Cell Phagocytic Capacity
- High evidence
- Highly Cited
- Elderly
Increases in PMN and NK cell activity were greatest among subjects who consumed B. lactis in lactose-hydrolysed LFM.
Effect
Beneficial
Effect size
Moderate
Significant
Yes
Dose
not specified
Enhancement of natural immune function by dietary consumption of Bifidobacterium lactis (HN019)
- 2000-03-01
- RCT · n = 25
- European Journal of Clinical Nutrition 54(3)
- - K. Arunachalam
  - H. Gill
  - R. Chandra
- PubMed: 10713750
- DOI: 10.1038/sj.ejcn.1600938
7 Insights on
- Increased PMN Cell Phagocytic Capacity
- High evidence
- Highly Cited
- Elderly
while individuals who consumed B. lactis-supplemented milk or milk alone showed enhanced phagocyte-mediated bactericidal activity.
Effect
Neutral
Effect size
Small
Significant
No
Dose
1.5×10^11 CFU twice daily