Dose-response effect of Bifidobacterium lactis HN019 on whole gut transit time and functional gastrointestinal symptoms in adults
- 2011-06-13
- RCT · n = 100
- Scandinavian Journal of Gastroenterology 46(9)
- Philip A Waller
- P. Gopal
- G. Leyer
- A. Ouwehand
- C. Reifer
- Morgan E Stewart
- L. Miller
- PubMed: 21663486
- DOI: 10.3109/00365521.2011.584895
- High evidence
- Highly Cited
Decreases in mean WGTT over the 14-day study period were statistically significant in the high dose group (49 ± 30 to 21 ± 32 h, p < 0.001) and the low dose group (60 ± 33 to 41 ± 39 h, p = 0.01), but not in the placebo group (43 ± 31 to 44 ± 33 h).
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes
- Dose
- 1.8 billion CFU/day