Bifidobacterium lactis MAK16B42L and Enhanced Natural Killer Cell Tumoricidal Activity

• The Effect of Bifidobacterium animalis ssp. lactis HN019 on Cellular Immune Function in Healthy Elderly Subjects: Systematic Review and Meta-Analysis

  • 2017-02-24
  • Meta-Analysis
  • Nutrients 9(3)
  • • L. Miller
    • L. Lehtoranta
    • M. Lehtinen

  • PubMed: 28245559
  • DOI: 10.3390/nu9030191

  5 Insights on

  • Enhanced Natural Killer Cell Tumoricidal Activity

  • High evidence
  • Elderly

  *B. lactis* HN019 supplementation was moderately efficacious in increasing NK cell tumoricidal activity with an SMD of 0.43 (95% confidence interval: 0.08 to 0.78, *p* = 0.02)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Enhancing immunity by dietary consumption of a probiotic lactic acid bacterium (Bifidobacterium lactis HN019): optimization and definition of cellular immune responses

  • 2000-11-01
  • RCT · n = 50
  • European Journal of Clinical Nutrition 54(11)
  • • B. Chiang
    • Y. Sheih
    • LH Wang
    • Chuh-K. Liao
    • H. Gill

  • PubMed: 11114680
  • DOI: 10.1038/sj.ejcn.1601093

  16 Insights on

  • Enhanced Natural Killer Cell Tumoricidal Activity

  • High evidence
  • Highly Cited
  • Elderly

  Increases in PMN and NK cell activity were greatest among subjects who consumed B. lactis in lactose-hydrolysed LFM.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  not specified