Bifidobacterium lactis MAK16B42L and Increased Intestinal Bifidobacterium Levels

• Effects of administration of Bifidobacterium animalis subsp. lactis GCL2505 on defecation frequency and bifidobacterial microbiota composition in humans.

  • 2012-05
  • RCT · n = 17
  • Journal of Bioscience and Bioengineering 113(5)
  • • Akihiro Ishizuka
    • K. Tomizuka
    • Ryo Aoki
    • Tomohiko Nishijima
    • Yasuo Saito
    • R. Inoue
    • K. Ushida
    • Takashi Mawatari
    • Takayuki Ikeda

  • PubMed: 22284965
  • DOI: 10.1016/j.jbiosc.2011.12.016

  21 Insights on

  • Increased Intestinal Bifidobacterium Levels

  • High evidence

  The aim of this study was to evaluate the changes in endogenous bifidobacteria and administered Bifidobacterium animalis subsp. lactis (B. lactis) GCL2505 (GCL2505) in the intestine after administration of GCL2505 by means of a randomized, placebo-controlled double-blind, cross-over study. An increase in the number of total bifidobacteria (the sum of B. bifidum, B. breve, B. longum subsp. longum, B. adolescentis, B. anglatum, B. catenulatum, B. pseudocatenulatum, B. dentium, B. longum subsp. infantis and B. lactis) in the feces were observed after administration of GCL2505 using species- and subspecies-specific real-time polymerase chain reaction analysis.

  Effect

  Beneficial

  Effect size

  Moderate