Bifidobacterium lactis MAK16B42L and Increased Stool Frequency

• Fermented Milk Containing Bifidobacterium lactis DN-173 010 in Childhood Constipation: A Randomized, Double-Blind, Controlled Trial

  • 2011-06-01
  • RCT · n = 159
  • Pediatrics 127(6)
  • • M. Tabbers
    • A. Chmielewska
    • M. Roseboom
    • N. Crastes
    • C. Perrin
    • J. Reitsma
    • O. Norbruis
    • H. Szajewska
    • M. Benninga

  • PubMed: 21606153
  • DOI: 10.1542/peds.2010-2590

  1 Insight on

  • Increased Stool Frequency

  • High evidence
  • Highly Cited

  The change in stool frequency from baseline to after 3 weeks of product consumption increased in both groups, but the difference was not statistically significant (2.9 ± 3.2 in probiotic group versus 2.6 ± 2.6 in control group, P = .35).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Effect of a fermented milk containing Bifidobacterium lactis DN-173010 on Chinese constipated women.

  • 2009-04-02
  • RCT
  • World Journal of Gastroenterology 14(40)
  • • Yue-xin Yang
    • M. He
    • Gang Hu
    • Jie Wei
    • P. Pagès
    • Xiankui Yang
    • S. Bourdu-Naturel

  • PubMed: 18985817
  • DOI: 10.3748/WJG.14.6237

  7 Insights on

  • Increased Stool Frequency

  • High evidence
  • Highly Cited
  • Clinical

  Following consumption of test product, stool frequency was significantly increased after 1 wk (3.5 +/- 1.5 vs 2.4 +/- 0.6, P < 0.01) and 2 wk (4.1 +/- 1.7 vs 2.4 +/- 0.6, P < 0.01), vs baseline.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes