Bifidobacterium longum MAK34B12L and Improved Acute Liver Injury

• Bifidobacterium longum BL-10 with Antioxidant Capacity Ameliorates Lipopolysaccharide-Induced Acute Liver Injury in Mice by the Nuclear Factor-κB Pathway.

  • 2022-07-07
  • Clinical Trial
  • Journal of Agricultural and Food Chemistry 70(28)
  • • Jiahuan Dong
    • Lijun Ping
    • Y. Meng
    • Kangyong Zhang
    • Hongwei Tang
    • Deyu Liu
    • Bailiang Li
    • G. Huo

  • PubMed: 35797025
  • DOI: 10.1021/acs.jafc.2c02950

  5 Insights on

  • Improved Acute Liver Injury

  • Low evidence
  • Animal Study

  The intragastric administration of *B. longum* BL-10 resulting in a marked reduction in liver function indicators (alanine aminotransferase, aspartate aminotransferase, total bilirubin, and total bile acid) and proinflammatory cytokines (TNF-α, IFN-γ, and IL-6) was indicative of ALI recovery.

  Effect

  Beneficial

  Effect size

  Large