Bifidobacterium longum MAK34B12L and Improved Bone Mass Density

• Probiotics (Bifidobacterium longum) Increase Bone Mass Density and Upregulate Sparc and Bmp-2 Genes in Rats with Bone Loss Resulting from Ovariectomy

  • 2016-06-09
  • RCT · n = 3
  • BioMed Research International 2015
  • • Kolsoom Parvaneh
    • M. Ebrahimi
    • M. Sabran
    • G. Karimi
    • Angela Ng Min Hwei
    • Saif Abdul-Majeed
    • Z. Ahmad
    • Z. Ibrahim
    • R. Jamaluddin

  • PubMed: 26366421
  • DOI: 10.1155/2015/897639

  4 Insights on

  • Improved Bone Mass Density

  • Low evidence
  • Highly Cited
  • Rigorous Journal
  • Animal Study

  Consequently, it increased BMD by increasing (p < 0.05) the expression of Sparc and Bmp-2 genes.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes