Bifidobacterium longum MAK34B12L and Improved Glucose Tolerance

• Bifidobacterium longum counters the effects of obesity: Partial successful translation from rodent to human

  • 2021-01
  • RCT
  • EBioMedicine 63
  • • H. Schellekens
    • C. Torres-Fuentes
    • M. van de Wouw
    • C. Long-Smith
    • A. Mitchell
    • C. Strain
    • K. Berding
    • T. Bastiaanssen
    • K. Rea
    • A. Golubeva
    • S. Arboleya
    • Mathieu Verpaalen
    • M. Pusceddu
    • A. Murphy
    • F. Fouhy
    • K. Murphy
    • P. Ross
    • Bernard L. Roy
    • C. Stanton
    • T. Dinan
    • J. Cryan

  • PubMed: 33349590
  • DOI: 10.1016/j.ebiom.2020.103176

  13 Insights on

  • Improved Glucose Tolerance

  • High evidence
  • Rigorous Journal

  B. longum APC1472 supplementation was associated with decreased bodyweight, fat depots accumulation and increased glucose tolerance in HFD-fed mice.

  Effect

  Beneficial

  Effect size

  Moderate

• Oral Probiotic Bifidobacterium Longum Supplementation Improves Metabolic Parameters and Alters the Expression of the Renin-Angiotensin System in Obese Mice Liver

  • 2020-07-23
  • RCT · n = 32
  • Biological Research For Nursing 23(1)
  • • A. S. Machado
    • J. R. Oliveira
    • D. F. Lelis
    • A. D. de Paula
    • A. Guimarães
    • J. Andrade
    • I. Brandi
    • S. Santos

  • PubMed: 32700545
  • DOI: 10.1177/1099800420942942

  6 Insights on

  • Improved Glucose Tolerance

  • Low evidence
  • Animal Study

  HFD + BL mice had a significant reduction in blood glucose during an intraperitoneal glucose tolerance test.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes