Bifidobacterium longum MAK34B12L and Improved Insulin Sensitivity

• Bifidobacterium longum with Fructo-Oligosaccharides in Patients with Non Alcoholic Steatohepatitis

  • 2011-09-08
  • RCT · n = 66
  • Digestive Diseases and Sciences 57(2)
  • • M. Malaguarnera
    • M. Vacante
    • T. Antić
    • M. Giordano
    • G. Chisari
    • R. Acquaviva
    • S. Mastrojeni
    • G. Malaguarnera
    • A. Mistretta
    • G. Volti
    • F. Galvano

  • PubMed: 21901256
  • DOI: 10.1007/s10620-011-1887-4

  17 Insights on

  • Improved Insulin Sensitivity

  • High evidence
  • Highly Cited
  • Rigorous Journal

  At the end of study period, we observed that the Bifidobacterium longum with Fos and lifestyle modification group versus the lifestyle modification alone group showed significant differences in the... HOMA-IR -1.1 versus -0.6 (P < 0.001)

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes

• The antidiabetic effects of Bifidobacterium longum subsp. longum BL21 through regulating gut microbiota structure in type 2 diabetic mice.

  • 2022-10-05
  • Clinical Trial
  • Food & Function 13(19)
  • • Junyu Hao
    • Yongli Zhang
    • Tao Wu
    • R. Liu
    • Wenjie Sui
    • Jiangu Zhu
    • S. Fang
    • Jieting Geng
    • M. Zhang

  • PubMed: 36056711
  • DOI: 10.1039/d2fo01109c

  7 Insights on

  • Improved Insulin Sensitivity

  • Low evidence
  • Animal Study

  Our data indicated that BL21 at a dose of 109 CFU per day significantly lowered the levels of fasting blood glucose and alleviated insulin resistance in diabetic mice.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes