Bifidobacterium longum SP54 and Reduced Prevalence of Gestational Diabetes Mellitus

• The effect of probiotic supplementation on the risk of gestational diabetes mellitus among high-risk pregnant women: A parallel double-blind, randomized, placebo-controlled clinical trial.

  • 2021-09
  • RCT · n = 271
  • Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie 141
  • • Ali Shahriari
    • Elham Karimi
    • Mohammadali Shahriari
    • Neda Aslani
    • Maryam Khooshideh
    • Arman Arab

  • PubMed: 34328109
  • DOI: 10.1016/j.biopha.2021.111915

  3 Insights on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • High evidence
  • Large Human Trial

  The incidence of GDM in the intervention group was 41.9% which was not significantly different from the control group (40.2%) (P = 0.780).

  Effect

  Neutral

  Effect size

  Small

  Significant

  No

• Probiotics for the prevention of gestational diabetes mellitus: A meta-analysis of randomized controlled trials.

  • 2024-09-06
  • Meta-Analysis
  • Biomolecules & biomedicine 24(5)
  • • Xue Li
    • Luwen Zhang
    • Yuanqi He
    • Dandan Zhang
    • Shihong Zhang

  • PubMed: 38642385
  • DOI: 10.17305/bb.2024.10377

  1 Insight on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • High evidence

  probiotics significantly reduced the incidence of GDM as compared to control (risk ratio [RR]: 0.71, 95% confidence interval [CI]: 0.52-0.96, P = 0.03)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• A Review of Modulation of Gut Microbiota to Mitigate Gestational Diabetes: Implications for Maternal and Child Health.

  • 2025-08-22
  • Review
  • Medical science monitor : international medical journal of experimental and clinical research 31
  • • Olimpia Mora-Janiszewska
    • Kinga Bialic
    • Anna Faryniak
    • Dorota Darmochwał-Kolarz

  • PubMed: 40842120
  • DOI: 10.12659/msm.948897

  3 Insights on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • Low evidence

  The aim of this article is to review the role of gut microbiota modulation in preventing and managing gestational diabetes mellitus and the health benefits for mother and child.

  Effect

  Beneficial

  Effect size

  Moderate

• Probiotics for preventing gestational diabetes in overweight or obese pregnant women: A review.

  • 2022-12-26
  • Review
  • World journal of clinical cases 10(36)
  • • Ya-Fang Deng
    • Li-Ping Wu
    • Yan-Ping Liu

  • PubMed: 36683622
  • DOI: 10.12998/wjcc.v10.i36.13189

  2 Insights on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • Low evidence

  Specific probiotics or probiotic foods may alter gut microbiota in overweight or obese pregnant women and inhibit the expression of inflammatory factors, consequently resulting in weight loss and reduced insulin resistance.

  Effect

  Beneficial

  Effect size

  Small