Best Supplements for Reduced Prevalence of Gestational Diabetes Mellitus
Ranked by research evidence. Compare 5 supplements across 12 papers from the biomedical literature, with effect direction, evidence strength, and dose range for each.
Top picks by evidence
- Moderate evidence4 studies
Across 4 studies, all reported beneficial effects of probiotics containing *Lactobacillus salivarius* UCC118 on reducing the prevalence of gestational diabetes mellitus, with a predominant moderate effect size. Two meta-analyses reported statistically significant reductions in GDM risk (risk ratios of 0.52 and 0.71). The evidence is drawn from pregnant women, but no specific dose range or study duration was consistently reported across the included studies.
- Low evidence4 studies
Across 4 studies, 3 reported beneficial effects (small to moderate) but only 1 (a meta-analysis) reached statistical significance; the highest-quality RCT found no significant benefit. The evidence is primarily from generic probiotic interventions, not specifically Bifidobacterium longum SP54, and effect sizes are mixed. The most studied population is pregnant women, particularly those at high risk or overweight/obese.
- ModerateLactobacillus salivarius UCC118Across 4 studies, all reported beneficial effects of probiotics containing *Lactobacillus salivarius* UCC118 on reducing the prevalence of gestational diabetes mellitus, with a predominant moderate effect size. Two meta-analyses reported statistically significant reductions in GDM risk (risk ratios of 0.52 and 0.71). The evidence is drawn from pregnant women, but no specific dose range or study duration was consistently reported across the included studies.4 beneficial4 studies
- LowBifidobacterium longum SP54Across 4 studies, 3 reported beneficial effects (small to moderate) but only 1 (a meta-analysis) reached statistical significance; the highest-quality RCT found no significant benefit. The evidence is primarily from generic probiotic interventions, not specifically Bifidobacterium longum SP54, and effect sizes are mixed. The most studied population is pregnant women, particularly those at high risk or overweight/obese.3 beneficial1 neutral4 studies