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Evidence-Based Supplement Research
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Lactobacillus salivarius UCC118 and Reduced Prevalence of Gestational Diabetes Mellitus

Research synthesisModerate evidenceModerate effect4 studies · 4 beneficial · 0 neutral · 0 harmful

Across 4 studies, all reported beneficial effects of probiotics containing *Lactobacillus salivarius* UCC118 on reducing the prevalence of gestational diabetes mellitus, with a predominant moderate effect size. Two meta-analyses reported statistically significant reductions in GDM risk (risk ratios of 0.52 and 0.71). The evidence is drawn from pregnant women, but no specific dose range or study duration was consistently reported across the included studies.

  • Studied populations: pregnant women

Caveats: Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Doses and study durations were not consistently reported, limiting the ability to specify an effective dose range or treatment duration.

Generated May 12, 2026
4 of 4 papers
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