Lactobacillus salivarius UCC118 and Reduced Prevalence of Gestational Diabetes Mellitus

• The effect of probiotics on gestational diabetes and its complications in pregnant mother and newborn: A systematic review and meta-analysis during 2010-2020.

  • 2022-03-03
  • Meta-Analysis · n = 4,865
  • Journal of clinical laboratory analysis 36(4)
  • • Marzie Mahdizade Ari
    • Samane Teymouri
    • Tayebeh Fazlalian
    • Parisa Asadollahi
    • Roghayeh Afifirad
    • Mohammad Sabaghan
    • Fateme Valizadeh
    • Roya Ghanavati
    • Atieh Darbandi

  • PubMed: 35243684
  • DOI: 10.1002/jcla.24326

  1 Insight on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • High evidence

  The present meta-analysis showed that the consumption of probiotics supplementation has the potential to decrease GD-predisposing metabolic parameters such as blood glucose level, lipid profile, inflammation, and oxidative markers which may reduce GD occurrence among pregnant women.

  Effect

  Beneficial

  Effect size

  Moderate

• Probiotics improve glucose and lipid metabolism in pregnant women: a meta-analysis.

  • 2019-03
  • Meta-Analysis · n = 139
  • Annals of translational medicine 7(5)
  • • Man-Man Han
    • Jin-Fang Sun
    • Xiang-Hui Su
    • You-Fan Peng
    • Hemant Goyal
    • Chun-Hua Wu
    • Xiang-Yun Zhu
    • Ling Li

  • PubMed: 31019949
  • DOI: 10.21037/atm.2019.01.61

  4 Insights on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • High evidence

  The study found a significant effect of probiotics on decreasing the risk of GDM [risk ratio (RR) 0.52, P=0.003) in early pregnancy.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Probiotics for the prevention of gestational diabetes mellitus: A meta-analysis of randomized controlled trials.

  • 2024-09-06
  • Meta-Analysis
  • Biomolecules & biomedicine 24(5)
  • • Xue Li
    • Luwen Zhang
    • Yuanqi He
    • Dandan Zhang
    • Shihong Zhang

  • PubMed: 38642385
  • DOI: 10.17305/bb.2024.10377

  1 Insight on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • High evidence

  probiotics significantly reduced the incidence of GDM as compared to control (risk ratio [RR]: 0.71, 95% confidence interval [CI]: 0.52-0.96, P = 0.03)

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Efficacy of dietary supplements targeting gut microbiota in the prevention and treatment of gestational diabetes mellitus.

  • 2022-07-14
  • Review
  • Frontiers in microbiology 13
  • • Jiayang Wan
    • Jingmei Ma

  • PubMed: 35910625
  • DOI: 10.3389/fmicb.2022.927883

  2 Insights on

  • Reduced Prevalence of Gestational Diabetes Mellitus

  • Low evidence

  This paper reviews a series of clinical trials in recent years, expounds on the clinical effects of dietary supplements such as probiotics on GDM... using dietary supplements, such as probiotics, prebiotics, and synbiotics to target the gut microbiota to regulate the disordered gut microbiota would become a potential method that benefits for preventing and treating GDM.

  Effect

  Beneficial

  Effect size

  Small