Multi-omics analyses the effect of Bifidobacterium longum subsp. longum BL21 supplementation on overweight and obese subjects: a randomized, double-blind, placebo-controlled study.

2025-07-17
RCT
Nutrition & metabolism 22(1)
- Xiaoya Wang
- Zefeng Xing
- Rui Wang
- Guoming Zhang
- Guodong Liu
- Zhen Li
- Lixiang Li

PubMed: 40676704
DOI: 10.1186/s12986-025-00969-2

Reduced Body Weight

High evidence

both the BL21 group ... and placebo group ... demonstrated significant body weight reductions, with no statistically significant intergroup difference observed

Effect: Neutral
Effect size: Small
Significant: No

Bifidobacterium longum subsp. longum and Reduced Body Weight

Multi-omics analyses the effect of Bifidobacterium longum subsp. longum BL21 supplementation on overweight and obese subjects: a randomized, double-blind, placebo-controlled study.