Bifidobacterium plantarum and Improved Neuroprotection

• Probiotic and microbial modulation of polyamine production: an emerging avenue for neuroprotection in neurodegenerative disorders.

  • 2026-02-21
  • Review
  • Amino acids 58(1)
  • • Tushar Adhikari
    • Prerona Saha

  • PubMed: 41721117
  • DOI: 10.1007/s00726-026-03505-5

  6 Insights on

  • Improved Neuroprotection

  • Low evidence

  Targeting microbiota-driven polyamine synthesis is emerging as a promising, non-invasive approach for neuroprotection

  Effect

  Beneficial

  Effect size

  Moderate

• Probiotics and Phytoantioxidants as Emerging Neuroprotective Strategies: Bridging the Therapeutic Gap in Open Heart Surgery-Induced Brain Injury.

  • 2026-02-26
  • Review
  • Biomedicines 14(3)
  • • Yen Chu
    • Kuo-Hsiung Huang
    • Chi-Nan Tseng

  • PubMed: 41898174
  • DOI: 10.3390/biomedicines14030527

  5 Insights on

  • Improved Neuroprotection

  • Low evidence

  Probiotics and phytoantioxidants have emerged as promising candidates because of their ability to modulate gut-brain axis signaling, reduce oxidative stress, and support vascular repair. Probiotics provide benefits by stabilizing intestinal microbiota, lowering systemic endotoxemia, and enhancing anti-inflammatory cytokine activity, thereby indirectly protecting neural tissue.

  Effect

  Beneficial

  Effect size

  Moderate