Modulation of gut-heart axis by synbiotic (Lactiplantibacillus plantarum M10 and Isomaltose) in high cholesterol diet induced atherosclerotic murine model.
- 2026-02-20
- BMC microbiology 26(1)
- Siloni Patial
- Khem Raj
- Geeta Shukla
- PubMed: 41721244
- DOI: 10.1186/s12866-026-04840-z
- Low evidence
Eighteen weeks of synbiotic supplementation to Sprague Dawley rats fed with high-cholesterol diet significantly attenuated anthropometric variables such as body weight, BMI, Lee’s Index, organ weight, blood glucose, and lipid profile... and reduced hepatic steatosis and aortic thickening.
- Effect
- Beneficial
- Effect size
- Large
- Significant
- Yes