Bifidobacterium plantarum and Reduced Gastrointestinal Symptoms

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all 3 reported beneficial moderate-sized effects of Bifidobacterium plantarum on reducing gastrointestinal symptoms. The evidence is drawn from review articles covering varied populations, including patients with chronic kidney disease, athletes, and general populations, but lacks information on specific doses, forms, or study durations.

Studied populations: patients with chronic kidney disease, athletes

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. All three studies are reviews, not primary clinical trials, and no individual study reported statistical significance or provided extractable dose/form data. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed).

Generated May 12, 2026

3 of 3 papers

Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review.
- 2026-03-24
- Review
- Frontiers in immunology 16
- - Mohamed T El-Saadony
  - Ahmed M Saad
  - Mahmoud Sitohy
  - Samar Sami Alkafaas
  - Mthokozisi Dladla
  - Soumya Ghosh
  - Dina Mostafa Mohammed
  - Essam H Ibrahim
  - Mohamed A Fahmy
  - Amr Elkelish
  - Synan F AbuQamar
  - Khaled A El-Tarabily
- PubMed: 41953220
- DOI: 10.3389/fimmu.2025.1713426
10 Insights on
- Reduced Gastrointestinal Symptoms
- Low evidence
The consumption of such products has been associated with the alleviation of disorders, including irritable bowel syndrome, lactose intolerance, gastroenteritis, obesity, chronic diarrhea, allergies, atopic dermatitis, and infectious diseases.
Effect
Beneficial
Effect size
Moderate
Microbiota management: a perspective for kidney transplant patients.
- 2026-02-19
- Review
- Frontiers in transplantation 5
- - Cláudia Silva Souza
  - Niels Olsen Saraiva Camara
  - Thaís Alves-Silva
- PubMed: 41798990
- DOI: 10.3389/frtra.2026.1703048
7 Insights on
- Reduced Gastrointestinal Symptoms
- Low evidence
Clinical studies have demonstrated that the combination of prebiotics, probiotics, and synbiotics-supplements that aid in the establishment of intestinal microbiota-can effectively help control the production of nitrogenous substances, reduce renal inflammation, and alleviate gastrointestinal symptoms in patients with CKD.
Effect
Beneficial
Effect size
Moderate
Probiotic supplementation for optimizing athletic performance: current evidence and future perspectives for microbiome-based strategies.
- 2025-07-15
- Review
- Frontiers in nutrition 12
- - Timea Teglas
  - Zsolt Radak
- PubMed: 40735239
- DOI: 10.3389/fnut.2025.1572687
10 Insights on
- Reduced Gastrointestinal Symptoms
- Low evidence
In endurance-based sports, probiotics enhanced lipid metabolites, including short-chain and polyunsaturated fatty acids, modulated the maximal oxygen capacity, and reduced gastrointestinal symptoms.
Effect
Beneficial
Effect size
Moderate

Bifidobacterium plantarum and Reduced Gastrointestinal Symptoms

Probiotics and human health: biological activities, nutritional aspects, immunomodulatory properties, applications, and future perspectives - a comprehensive review.

Microbiota management: a perspective for kidney transplant patients.

Probiotic supplementation for optimizing athletic performance: current evidence and future perspectives for microbiome-based strategies.