Lacticaseibacillus casei R0215 and Reduced Crying Duration

• Nine-Strain Bacterial Synbiotic Improves Crying and Lowers Fecal Calprotectin in Colicky Babies-An Open-Label Randomized Study.

  • 2022-02-12
  • RCT · n = 50
  • Microorganisms 10(2)
  • • Malgorzata Bernatek
    • Jacek Piątek
    • Marcin Pszczola
    • Hanna Krauss
    • Janina Antczak
    • Paweł Maciukajć
    • Henning Sommermeyer

  • PubMed: 35208884
  • DOI: 10.3390/microorganisms10020430

  2 Insights on

  • Reduced Crying Duration

  • High evidence

  Administration of the synbiotic resulted in a rechange of crying duration of -7.18 min/day of treatment, while simethicone had a significantly smaller effect (-5.74 min/day).

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes