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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lacticaseibacillus casei and Improved Bowel Movement Frequency

Doses used in studies

cfu/day: 100 million (median 100 million, IQR 100 million–100 million) — 1 study

2 of 2 papersPopulation:

Probiotics and synbiotics in chronic constipation in adults: A systematic review and meta-analysis of randomized controlled trials.
- 2022-12
- Meta-Analysis
- Clinical nutrition (Edinburgh, Scotland) 41(12)
- - Alice van der Schoot
  - Carina Helander
  - Kevin Whelan
  - Eirini Dimidi
- PubMed: 36372047
- DOI: 10.1016/j.clnu.2022.10.015
1 Insight on
- Improved Bowel Movement Frequency
- High evidence
- Clinical
with Bifidobacterium lactis having a significant effect, but not mixtures of probiotics, Bacillus coagulans Unique IS2 or Lactobacillus casei Shirota.
Effect
Neutral
Effect size
Small
Significant
No
Recovery of Lactobacillus casei strain Shirota (LcS) from faeces of healthy Singapore adults after intake of fermented milk.
- 2019-10-14
- Beneficial Microbes 10(7)
- - W. W. T. Khine
  - X. Ang
  - Y. S. Chan
  - W. Q. Lee
  - S. Quek
  - S. H. Tan
  - H. T. A. Teo
  - J. Teo
  - Q. Lau
  - Y.K. Lee
- PubMed: 31965844
- DOI: 10.3920/BM2018.0173
7 Insights on
- Improved Bowel Movement Frequency
- Low evidence
- Adults
the composition of the major gut microbiota ... and characteristics of defaecation such as stool consistency and frequency of defecation did not change throughout the study before and after ingestion of LcS.
Effect
Neutral
Effect size
Small
Significant
No
Dose
1.0×10^8 cfu/ml, 100 ml daily