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Evidence-Based Supplement Research

Evidence-Based Supplement Research

Lacticaseibacillus casei and Reduced Interleukin-6 Levels

Doses used in studies

cells/day: 13 billion (median 13 billion, IQR 13 billion–13 billion) — 1 study

Time to effect

Median: 3.3 months · IQR 3.3 months–3.3 months · Range 3.3 months–3.3 months — Reported in 1 of 1 study

1 of 1 paper

Immune Response of Healthy Adults to the Ingested Probiotic Lactobacillus casei Shirota.
- 2016-12
- Clinical Trial
- Scandinavian journal of immunology 84(6)
- - L S Harbige
  - E Pinto
  - J Allgrove
  - L V Thomas
- PubMed: 27718254
- DOI: 10.1111/sji.12495
10 Insights on
- Reduced Interleukin-6 Levels
- Moderate evidence
- Adults
Intracellular staining of IL-12 in ex vivo unstimulated and LPS-stimulated CD14+ blood cells was significantly lower at weeks 4, 10 and 14
Effect
Beneficial
Effect size
Small
Significant
Yes
Dose
1.3 × 10^10 live cells/day