Lacticaseibacillus casei and Reduced Physical Symptoms

• Probiotic Lactobacillus casei strain Shirota relieves stress-associated symptoms by modulating the gut-brain interaction in human and animal models.

  • 2016-02-20
  • RCT
  • Neurogastroenterology and motility 28(7)
  • • M Takada
    • K Nishida
    • A Kataoka-Kato
    • Y Gondo
    • H Ishikawa
    • K Suda
    • M Kawai
    • R Hoshi
    • O Watanabe
    • T Igarashi
    • Y Kuwano
    • K Miyazaki
    • K Rokutan

  • PubMed: 26896291
  • DOI: 10.1111/nmo.12804

  3 Insights on

  • Reduced Physical Symptoms

  • High evidence
  • Highly Cited
  • Adults

  Academic stress-induced increases in salivary cortisol levels and the incidence rate of physical symptoms were significantly suppressed in the LcS group compared with the placebo group.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

  Dose

  daily for 8 weeks