Lactiplantibacillus plantarum KABP-022 and Improved Vascular Function in Offspring

• Lactiplantibacillus plantarum WJL administration during pregnancy and lactation improves lipid profile, insulin sensitivity and gut microbiota diversity in dyslipidemic dams and protects male offspring against cardiovascular dysfunction in later life.

  • 2021-05-14
  • RCT · n = 15
  • Food & Function 11(10)
  • • K. Guimarães
    • V. Braga
    • S. Noronha
    • Whyara K A Costa
    • Kassem Makki
    • J. Cruz
    • Larissa Ramalho Brandão
    • Deoclecio Alves Chianca Junior
    • E. Meugnier
    • F. Leulier
    • H. Vidal
    • M. Magnani
    • J. L. de Brito Alves

  • PubMed: 33000822
  • DOI: 10.1039/d0fo01718c

  8 Insights on

  • Improved Vascular Function in Offspring

  • Low evidence
  • Animal Study
  • Clinical

  In contrast, male offspring of DLP-LpWJL dams had reduced blood pressure and recovered vascular function in later life.

  Effect

  Beneficial

  Effect size

  Moderate