Lactiplantibacillus plantarum KABP-023 and Reduced Body Mass Index

• Effects of the probiotic Lactiplantibacillus plantarum IMC 510® on body composition, biochemical parameters, gut microbiota composition and function, and clinical symptoms of overweight/obese subjects

  • 2023-04-11
  • RCT · n = 40
  • Frontiers in Nutrition 10
  • • G. Pagliai
    • M. Coman
    • S. Baldi
    • M. Dinu
    • G. Nannini
    • E. Russo
    • Lavinia Curini
    • B. Colombini
    • S. Lotti
    • M. Pallecchi
    • L. Di Gloria
    • G. Bartolucci
    • M. Ramazzotti
    • M. Verdenelli
    • F. Sofi
    • A. Amedei

  • PubMed: 37125045
  • DOI: 10.3389/fnut.2023.1142527

  12 Insights on

  • Reduced Body Mass Index

  • High evidence
  • Clinical

  Compared to placebo, probiotic supplementation determined a significant decrease in... BMI...

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes

• Supplementation with Lactiplantibacillus plantarum IMC 510 Modifies Microbiota Composition and Prevents Body Weight Gain Induced by Cafeteria Diet in Rats

  • 2021-10-16
  • Clinical Trial
  • International Journal of Molecular Sciences 22(20)
  • • M. V. Micioni Di Bonaventura
    • M. Coman
    • D. Tomassoni
    • E. Micioni Di Bonaventura
    • L. Botticelli
    • M. G. Gabrielli
    • G. Rossolini
    • V. di Pilato
    • C. Cecchini
    • A. Amedei
    • S. Silvi
    • M. Verdenelli
    • C. Cifani

  • PubMed: 34681831
  • DOI: 10.3390/ijms222011171

  11 Insights on

  • Reduced Body Mass Index

  • Low evidence
  • Animal Study
  • Clinical

  Accordingly, it ameliorated body mass index, liver and white adipose tissue weight, hepatic lipid accumulation, adipocyte size, serum parameters, including glycemia and low-density lipoprotein levels, in CAF fed rats, potentially through leptin control.

  Effect

  Beneficial

  Effect size

  Large