Lactobacillus acidophilus L-92 and Improved Cell-mediated Immunity

• The crosstalk between probiotics and T cell immunity.

  • 2025-10-23
  • Review
  • Frontiers in immunology 16
  • • Yuanyuan Liu
    • Xu Cao
    • Hongwei Liu
    • Wencan Zhang

  • PubMed: 41208998
  • DOI: 10.3389/fimmu.2025.1695840

  4 Insights on

  • Improved Cell-mediated Immunity

  • Low evidence

  Focusing on the T cell mediated responses and diseases, this review specifically aims to elucidate the intricate crosstalk between probiotic microorganisms and T cells, exploring how probiotics modulate the differentiation, activation, proliferation, and functional states of different T cell subsets, such as CD4+ T cells and CD8+ T cells, thereby influencing the overall immune response and immune homeostasis.

  Effect

  Beneficial

  Effect size

  Moderate