Across 4 studies, all reported beneficial effects of Lactobacillus acidophilus L-92 on increased antioxidant activity, with a predominant moderate effect size. The evidence is based entirely on reviews and lacks statistical significance testing, with no specific dose, population, or duration data available. The most commonly observed mechanism involves enhanced antioxidant enzyme activity and biotransformation of polyphenols.
Caveats: Evidence base is small (only 4 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). All studies are reviews with no original experimental data; none reported statistical significance, effect size estimates, or sample sizes, limiting the reliability of the findings.
microbial fermentation consistently increases TPC and enhances antioxidant activity
Specific probiotic strains exert their functions via mechanisms such as increasing immunoglobulin levels, suppressing the expression of inflammatory factors, and boosting antioxidant enzyme activity.
It highlights microbial-driven biotransformation of polyphenols and flavonoids, which enhances antioxidant activity and bioavailability.
The extracted PEPs exhibited significant scavenging activity against DPPH, ABTS, and hydroxyl radicals, as well as robust total reducing capacity.