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Evidence-Based Supplement Research
Evidence-Based Supplement Research
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Lactobacillus acidophilus La-14 and Reduced Inflammation

Research synthesisLow evidenceModerate effect3 studies · 3 beneficial · 0 neutral · 0 harmful

Across 3 studies, all reported beneficial effects on inflammation, with effect sizes ranging from small to moderate. The evidence is strongest for populations with gestational diabetes mellitus (GDM), where moderate effects on inflammatory markers (e.g., CRP, IL-6) were observed. No consistent dose or study duration was reported across the studies.

  • Studied populations: women with gestational diabetes mellitus (GDM), mouse model of colitis

Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). None of the studies reported statistical significance, and two of the three studies are reviews or animal-model research, limiting direct applicability to human supplementation.

Generated Jul 12, 2026
3 of 3 papers
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