Lactobacillus acidophilus NCFM and Reduced Visceral Hypersensitivity

• A Synbiotic Combining Chitin-Glucan and Lactobacillus acidophilus NCFM Induces a Colonic Molecular Signature Soothing Intestinal Pain and Inflammation in an Animal Model of IBS.

  • 2024-10-05
  • International journal of molecular sciences 25(19)
  • • Lena Capirchio
    • Christel Rousseaux
    • Caroline Dubuquoy
    • Arthur C Ouwehand
    • Véronique Maquet
    • Salvatore Modica
    • Edouard Louis
    • Pierre Desreumaux
    • Jan Tack

  • PubMed: 39409061
  • DOI: 10.3390/ijms251910732

  2 Insights on

  • Reduced Visceral Hypersensitivity

  • Low evidence
  • Rigorous Journal
  • Animal Study

  CG 1.5 alone and NCFM 10^9 colony forming units (CFU) alone similarly decreased the visceral pain sensitivity. The best profile of pain perception inhibition was obtained with the combination of CG 1.5 g and NCFM 10^9 CFU

  Effect

  Beneficial

  Effect size

  Moderate