Lactobacillus acidophilus R0418 and Reduced Diarrhea Frequency

• A Systematic Review and Meta-Analysis: Lactobacillus acidophilus for Treating Acute Gastroenteritis in Children

  • 2022-02-06
  • Meta-Analysis
  • Nutrients 14(3)
  • • Haixin Cheng
    • Yi Ma
    • Xiaohui Liu
    • Chao Tian
    • Xuli Zhong
    • Libo Zhao

  • PubMed: 35277042
  • DOI: 10.3390/nu14030682

  3 Insights on

  • Reduced Diarrhea Frequency

  • High evidence

  Lactobacillus acidophilus reduced the frequency of diarrhea on day 2 to day 5. However, it was statistically significant on day 3. When administered at a dosage of more than 109 CFU to children with acute gastroenteritis, moderate- to low-quality data showed that Lactobacillus acidophilus reduced the duration of diarrhea and conferred a benefit for frequency of diarrhea.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes