Lactobacillus acidophilus UALa01 and Improved Abdominal Pain Severity

• Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial

  • 2020-01-30
  • RCT · n = 330
  • Nutrients 12(2)
  • • C. Martoni
    • S. Srivastava
    • G. Leyer

  • PubMed: 32019158
  • DOI: 10.3390/nu12020363

  7 Insights on

  • Improved Abdominal Pain Severity

  • High evidence
  • Large Human Trial

  Over the intervention period, APS-NRS was significantly improved in both probiotic groups vs. placebo in absolute terms (DDS-1: -2.59 ± 2.07, p = 0.001; UABla-12: -1.56 ± 1.83, p = 0.001) and in percentage of significant responders (DDS-1: 52.3%, p < 0.001); UABla-12 (28.2%, p = 0.031).

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes