Lactobacillus acidophilus UALa01 and Reduced Irritable Bowel Syndrome Symptom Severity

• Lactobacillus acidophilus DDS-1 and Bifidobacterium lactis UABla-12 Improve Abdominal Pain Severity and Symptomology in Irritable Bowel Syndrome: Randomized Controlled Trial

  • 2020-01-30
  • RCT · n = 330
  • Nutrients 12(2)
  • • C. Martoni
    • S. Srivastava
    • G. Leyer

  • PubMed: 32019158
  • DOI: 10.3390/nu12020363

  7 Insights on

  • Reduced Irritable Bowel Syndrome Symptom Severity

  • High evidence
  • Large Human Trial

  Significant amelioration vs. placebo was observed in IBS Symptom Severity Scale (IBS-SSS) scores for L. acidophilus DDS-1 (-133.4 ± 95.19, p < 0.001) and B. lactis UABla-12 (-104.5 ± 96.08, p < 0.001) groups, including sub-scores related to abdominal pain, abdominal distension, bowel habits and quality of life.

  Effect

  Beneficial

  Effect size

  Large

  Significant

  Yes