Lactobacillus brevis MAK11L82B and Improved Intestinal Barrier Function

• Lactobacillus brevis DM9218 ameliorates fructose-induced hyperuricemia through inosine degradation and manipulation of intestinal dysbiosis.

  • 2019-06
  • Clinical Trial
  • Nutrition 62
  • • Haina Wang
    • L. Mei
    • Ying Deng
    • Yinhui Liu
    • Xiaoqing Wei
    • Man Liu
    • J. Zhou
    • Hong-Peng Ma
    • P. Zheng
    • Jieli Yuan
    • Ming Li

  • PubMed: 30852460
  • DOI: 10.1016/j.nut.2018.11.018

  5 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Animal Study

  The modulation effect of DM9218 on high-fructose-induced intestinal dysbiosis resulted in enhancement of intestinal barrier function and reduction of liver lipopolysaccharide...

  Effect

  Beneficial

  Effect size

  Moderate

• Oral administration of heat-killed Lactobacillus brevis SBC8803 ameliorates alcoholic liver disease in ethanol-containing diet-fed C57BL/6N mice.

  • 2008-12
  • Clinical Trial
  • International Journal of Food Microbiology 128(2)
  • • S. Segawa
    • Yoshihisa Wakita
    • H. Hirata
    • J. Watari

  • PubMed: 18976829
  • DOI: 10.1016/j.ijfoodmicro.2008.09.023

  22 Insights on

  • Improved Intestinal Barrier Function

  • Low evidence
  • Highly Cited
  • Animal Study

  We speculate...enhancement of intestinal barrier function by the induction of cytoprotective Hsps.

  Effect

  Beneficial

  Effect size

  Moderate