How Microbes Affect Depression: Underlying Mechanisms via the Gut-Brain Axis and the Modulating Role of Probiotics.
- 2022-01-21
- Review
- International journal of molecular sciences 23(3)
- Kazunori Suda
- Kazunori Matsuda
- PubMed: 35163104
- DOI: 10.3390/ijms23031172
- Moderate evidence
- Rigorous Journal
This review summarizes the current understanding of the molecular mechanisms involved in MDD onset, and discusses the therapeutic potential of probiotics, including butyrate-producing bacteria, which can mediate the microbiota-gut-brain axis.
- Effect
- Beneficial
- Effect size
- Small