Across 3 studies (all reviews), all reported small beneficial effects of Lactobacillus brevis SBC8803 on immune function, including enhanced natural killer cell activity and increased secretory IgA levels. The evidence base is very small, with no statistically significant findings reported, and no consistent dose, duration, or form data are available.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed). None of the included studies reported statistical significance or provided dose/duration details, limiting the practical applicability of findings.
Lactobacillus brevis SBC8803 has also been shown to enhance natural killer (NK) cell activity and increase secretory IgA levels
Lactobacillus brevis SBC8803 was reported as a probiotic/postbiotic component with positive effects on human health, and the review notes that such components can affect the immune response by providing host defenses against infection or suppressing inflammation.
it was observed that citrus fruits have great potential for the development of functional foods due to their high acceptability and possibilities of development and application in various products.