Across 3 review studies, all reported beneficial but small effects of Lactobacillus brevis SBC8803 on immune function, including enhanced natural killer cell activity and increased secretory IgA levels. No statistically significant findings were reported, and study durations, doses, and forms were not consistently documented. The evidence base is limited to reviews, with no original clinical trials available for this specific strain-outcome pair.
Caveats: Evidence base is small (only 3 studies) — conclusions should be considered preliminary. All three studies are literature reviews, not original clinical trials, limiting causal inference. Doses, durations, and forms were not reported in any study. Available evidence is overwhelmingly positive — clinical literature in this area is subject to publication bias (null-result studies are less likely to be published or indexed).
Lactobacillus brevis SBC8803 has also been shown to enhance natural killer (NK) cell activity and increase secretory IgA levels
Lactobacillus brevis SBC8803 was reported as a probiotic/postbiotic component with positive effects on human health, and the review notes that such components can affect the immune response by providing host defenses against infection or suppressing inflammation.
it was observed that citrus fruits have great potential for the development of functional foods due to their high acceptability and possibilities of development and application in various products.