Lactobacillus brevis SBC8803 and Reduced Liver Injury

• Targeting the gut barrier for the treatment of alcoholic liver disease.

  • 2017-12
  • Review
  • Liver research (Beijing, China) 1(4)
  • • Zhanxiang Zhou
    • Wei Zhong

  • PubMed: 30034913
  • DOI: 10.1016/j.livres.2017.12.004

  4 Insights on

  • Reduced Liver Injury

  • Low evidence

  Nutrient-based treatments, such as dietary supplementation with zinc, niacin or fatty acids, have been shown to regulate tight junction expression, reduce intestinal inflammation, and prevent endotoxemia as well as liver injury caused by alcohol in experimental settings.

  Effect

  Beneficial

  Effect size

  Moderate

• Levilactobacillus brevis MG5311 Alleviates Ethanol-Induced Liver Injury by Suppressing Hepatic Oxidative Stress in C57BL/6 Mice.

  • 2022-12-15
  • Microorganisms 10(12)
  • • Hyunna Jung
    • Sohyeon You
    • Soo-Im Choi
    • Chang-Ho Kang
    • Gun-Hee Kim

  • PubMed: 36557739
  • DOI: 10.3390/microorganisms10122488

  5 Insights on

  • Reduced Liver Injury

  • Low evidence

  L. brevis MG5311 administration significantly reduced serum ALT, AST, and triglyceride (TG) levels in ethanol-fed mice... hepatic TG content and histopathological scores were significantly reduced.

  Effect

  Beneficial

  Effect size

  Moderate

  Significant

  Yes