The relationship between intestinal flora and androgen level, glucose and lipid metabolism, inflammatory response and reproductive hormones: a systematic review and meta-analysis.
- 2026-03-04
- Systematic Review · n = 1,144
- BMC endocrine disorders 26(1)
- Lin Guo
- Yangxin Sun
- Conghui Pang
- Gaihong Liu
- PubMed: 41782088
- DOI: 10.1186/s12902-025-02153-2
- High evidence
We found that changes in gut microbiota can significantly improve glucose metabolism and lower fasting blood glucose levels[(MD): − 0.72 (- 1.22, −0.21), p < 0.01], Fasting insulin levels [(MD:-1.71 (- 2.60, − 0.83), p < 0.01)], homeostasis model assessment-insulin resistance [(MD: − 0.96 (- 1.72, − 0.21), p = 0.01)].
- Effect
- Beneficial
- Effect size
- Moderate
- Significant
- Yes